HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine → 3-((3R)-4-{2-[(1S)-6-Bromo-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl}-3-methylpiperazinyl)-1-benzothiophene-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine | HCID 69306552 | — |
| Reactant | 2-((1S)-6-Bromo-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate | HCID 86596021 | — |
| Product | 3-((3R)-4-{2-[(1S)-6-Bromo-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl}-3-methylpiperazinyl)-1-benzothiophene-6-carbonitrile | HCID 69307367 | — |
Reaction Steps
The title compound was prepared from 2-((1S)-6-bromo-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate and (3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine, as described for Example 1b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335660B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-d6effc451a6c4b2285361be2c4264036 |
| Source note | uspto-grants-2008_02 |