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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2056776Generated: October 30, 2026

Methanesulfonyl chloride → 2-((1S)-6-(2-Oxo-imidazolidin-1-yl)-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate

https://huagongshe.com/reaction/2056776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant3-[(1S)-1-(2-Hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-yl]-1,3-oxazolidin-2-oneHCID 69307290—
Reactant2-[(1S)-6-(aminocarbonyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonateHCID 86596012—
Product2-((1S)-6-(2-Oxo-imidazolidin-1-yl)-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonateHCID 86596022—

Reaction Steps

Prepared from 3-[(1S)-1-(2-hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-yl]-1,3-oxazolidin-2-one and methanesulfonyl chloride, as described for the preparation of 2-[(1S)-6-(aminocarbonyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonate

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07335660B2
Source datasetuspto-grants-2008_02
ORD IDord-24cebdf0789045eab49e02249c2b55ba
Source noteuspto-grants-2008_02