HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine → 1-((1S)-1-{2-[(2R)-4-(6-Cyano-1-benzothien-3-yl)-2-methylpiperazinyl]ethyl}-3,4-dihydro-1H-2-benzopyran-6-yl)-2-imidazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine | HCID 69306552 | — |
| Reactant | 2-((1S)-6-(2-Oxo-imidazolidin-1-yl)-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate | HCID 86596022 | — |
| Product | 1-((1S)-1-{2-[(2R)-4-(6-Cyano-1-benzothien-3-yl)-2-methylpiperazinyl]ethyl}-3,4-dihydro-1H-2-benzopyran-6-yl)-2-imidazolidinone | HCID 69307816 | — |
Reaction Steps
The title compound was prepared by condensation of 2-((1S)-6-(2-oxo-imidazolidin-1-yl)-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate and (3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine, as described for Example 1b). M+H=502.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335660B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-5cddde34700d40a1826f5ab2651c7a36 |
| Source note | uspto-grants-2008_02 |