HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine → 3-((3R)-3-Methyl-4-{2-[(1S)-6-(4-thiomorpholinyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl}piperazinyl)-1-benzothiophene-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine | HCID 69306552 | — |
| Reactant | 2-[(1S)-6-(4-Thiomorpholinyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonate | HCID 86596023 | — |
| Product | 3-((3R)-3-Methyl-4-{2-[(1S)-6-(4-thiomorpholinyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl}piperazinyl)-1-benzothiophene-6-carbonitrile | HCID 69310130 | — |
Reaction Steps
Prepared by condensation of 2-[(1S)-6-(4-thiomorpholinyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonate with (3R)-1-(6-cyano-1-benzothien-3-yl)-3-methylpiperazine, as described for Example 1b). M+H=519.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335660B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-1e016da1bdcd4b99a35ce64124a119c9 |
| Source note | uspto-grants-2008_02 |