HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenemethanamine, 3,4-dichloro- → N-(3,4-dichlorobenzyl)-N'-(3-methylcinnolin-5-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenemethanamine, 3,4-dichloro- | HCID 1608 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2,2,2-trichloro-N-(3-methylcinnolin-5-yl)acetamide | HCID 22032658 | — |
| Product | N-(3,4-dichlorobenzyl)-N'-(3-methylcinnolin-5-yl)urea | HCID 10406258 | — |
Reaction Steps
The title compound was prepared using 3,4-dichlorobenzylamine, the product from Example 16A, DBU and the procedure described in Example 1B. MS (ESI+) m/z 362 (M+H)+; 1H NMR (DMSO-d6) δ 2.88 (s, 3H), 4.36 (d, 2H), 7.10 (t, 1H), 7.34 (dd, 1H), 7.59 (m, 2H), 7.76 (t, 1H), 8.04 (d, 2H), 8.19 (d, 1H), 8.93 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335678B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-be1ac18af9d3429f8b3bf88da4cef816 |
| Source note | uspto-grants-2008_02 |