5-Bromo-8-nitroisoquinoline → Isoquinolin-8-amine

HRID 2056799Notes

Reaction equation

HRID 2056799 reaction equation
Br[C:2]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]=[CH:7]2>[Pd]>[CH:7]1[C:8]2[C:3](=[CH:2][CH:11]=[CH:10][C:9]=2[NH2:12])[CH:4]=[CH:5][N:6]=1

Participants

3

Reactant 1

HCID 8169835-Bromo-8-nitroisoquinoline

Product 1

HCID 13927912Isoquinolin-8-amine

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The product from Example 57B was treated with Pd/C under a hydrogen atmosphere to provide the title compound.

Sources & evidence

ORD record
ord-a32286ceb7c34cf1a4808170afd0e391
Source dataset
uspto-grants-2008_02
Patent number
US07335678B2

Reaction notes

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