HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2057047Generated: October 30, 2026
P-Phenylenediamine → N-(4-Aminophenyl)maleimide
https://huagongshe.com/reaction/2057047
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | P-Phenylenediamine | HCID 7814 | — |
| Reactant | Maleic Anhydride | HCID 7923 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(4-Aminophenyl)maleimide | HCID 122469 | 98.6% |
Reaction Steps
The solution of 21.6 g (200 mmol) of 1,4-phenylenediamine in 200 ml of tetrahydrofuran is mixed over 1.5 hours with the solution of 19.6 g of maleic acid anhydride, and it is stirred for 22 hours at 23° C. It is filtered, rewashed with tetrahydrofuran, and the filtrate is dried. 37.1 g (197 mmol, 98%) of the title compound is isolated as a crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07335775B2 |
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| Source dataset | uspto-grants-2008_02 |
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| ORD ID | ord-929bcb8435194c3c8d4075d699a2972b |
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| Source note | uspto-grants-2008_02 |
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