Potassium Cation → 5-(2-Chlorophenyl)-4-(4-chlorophenyl)-2-fluoropyridine

HRID 205712Notes

Reaction equation

HRID 205712 reaction equation
[Cl:16][c:17]1[c:18]([B:23]([OH:24])[OH:25])[cH:19][cH:20][cH:21][cH:22]1.[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[cH:4][c:5]([F:8])[n:6][cH:7]1.[K+:31].[K+:32].[K+:33].[O:36]=[C:37]([CH:38]=[CH:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)[CH:46]=[CH:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1.[O:54]=[C:55]([CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1)[CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1.[O:72]=[C:73]([CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1)[CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1.[P:26]([O-:27])([O-:28])([O-:29])=[O:30].[Pd:34].[Pd:35]>>[c:2]1(-[c:18]2[c:17]([Cl:16])[cH:22][cH:21][cH:20][cH:19]2)[c:3](-[c:9]2[cH:10][cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[cH:4][c:5]([F:8])[n:6][cH:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 23938Palladium2×HCID 95417Dibenzylidene acetone3×HCID 27343222-Chlorophenylboronic acidHCID 577994555-Chloro-4-(4-chlorophenyl)-2-fluoropyridine

Product 1

HCID 577994125-(2-Chlorophenyl)-4-(4-chlorophenyl)-2-fluoropyridine

Sources & evidence

ORD record
ord-7886616a40a241ba9843332eb73519ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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