Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205717Generated: October 27, 2026

Water → 7-(9'-cyclopentyl-5'-methyl-6'-oxo-5',6',8',9'-tetrahydrospiro[cyclopropane-1,7'-pyrimido[5,4-b][1,4]diazepine]-2'-ylamino)-N-(1-methyl-4-piperidyl)benzo[1,3]dioxole-4-carboxamide

https://huagongshe.com/reaction/205717

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactantp-Toluenesulfonic acidHCID 6101—
Reactant4-Methyl-2-PentanolHCID 7910—
Reactant2-chloro-9-cyclopentyl-8,9-dihydro-5-methylspiro[5H-pyrimido[4,5-b][1,4]diazepine-7,1'-cyclopropan]-6(7H)-oneHCID 57969939—
Reactant7-amino-N-(1-methyl-4-piperidyl)benzo[1,3]dioxole-4-carboxamideHCID 68681393—
Product7-(9'-cyclopentyl-5'-methyl-6'-oxo-5',6',8',9'-tetrahydrospiro[cyclopropane-1,7'-pyrimido[5,4-b][1,4]diazepine]-2'-ylamino)-N-(1-methyl-4-piperidyl)benzo[1,3]dioxole-4-carboxamideHCID 68682217—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6aefc922e8074e5e975f67573f5e916e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)