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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2057305Generated: October 26, 2026

Trifluoroacetic acid → HCID 178457218, compound

https://huagongshe.com/reaction/2057305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-MethylpropylamineHCID 12315—
Reactant4-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2777399—
ReactantHCID 178484800HCID 178484800—
ProductHCID 178457218HCID 178457218—

Reaction Steps

In analogy to examples 31.5 and 31.6, trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester.trifluoro-acetic acid and 4-trifluoromethyl-phenyl-sulfonylchloride were reacted, followed by treatment with methyl-propyl-amine to give trans-N-Methyl-N-{4-[4-(methyl-propyl-amino)-butyl]-cyclohexyl}-4-trifluoromethyl-benzenesulfonamide, MS: 449 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07335687B2
Source datasetuspto-grants-2008_02
ORD IDord-edcc4aebdbf647a7afdfe85abea2b3eb
Source noteuspto-grants-2008_02