HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178486040, compound → HCID 178486042, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178486040 | HCID 178486040 | — |
| Catalyst | Platinum dioxide monohydrate | HCID 11139377 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178486042 | HCID 178486042 | 101.4% |
Reaction Steps
A suspension of 3.4 g (12.72 mmol) of trans-[4-(3-Hydroxy-prop-1-ynyl)-cyclohexyl]-methyl-carbamic acid tert-butyl ester in 125 ml ethanol and 810 mg of PtO2.H2O was hydrogenated (1 atm) for 7 h. The reaction was filtered (Celite) and evaporated to give 3.5 g (quantitative) of trans-[4-(3-Hydroxy-propyl)-cyclohexyl]-methyl-carbamic acid tert-butyl ester, MS: 271 (MH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335687B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-5b2c2d4d644c403b9b0ed43bc0c367e9 |
| Source note | uspto-grants-2008_02 |