HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → 2,6-Diethyl-1,2,3,6-tetramethyl-4-[(trimethylsilyl)oxy]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Diethyl-1,2,3,6-tetramethylpiperidin-4-ol | HCID 20270966 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2,6-Diethyl-1,2,3,6-tetramethyl-4-[(trimethylsilyl)oxy]piperidine | HCID 20331877 | — |
Reaction Steps
21.1 g of 1,2,3,6-tetramethyl-2,6-diethyl-4-hydroxypiperidine and 20 g of triethylamine are dissolved in 250 ml of dioxane. By addition of 10.9 g of trimethylchlorosilane and using the same procedure of reaction and isolation as described in the previous examples there is obtained 1,2,3,6-tetramethyl-2,6-diethyl-4-(trimethylsiloxy)-piperidine (Compound No. 6), b.p. 78°-79° C./0.35 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04210578 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-4fe52d30b88d4315a7997ed0eda68609 |
| Source note | uspto-grants-1980_07 |