HCID 6486732, compound → 4-(3-Aminobutyl)benzonitrile

HRID 2057393Notes

Reaction equation

HRID 2057393 reaction equation
[CH3:1][CH:2]([NH2:12])[CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8](Cl)=[CH:7][CH:6]=1.[C:13](C1C=CC(CCC(=O)C)=CC=1)#[N:14]>>[CH3:1][CH:2]([NH2:12])[CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C:13]#[N:14])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 6486732HCID 6486732, compoundHCID 112982374-(3-Oxobutyl)benzonitrile

Product 1

HCID 537774914-(3-Aminobutyl)benzonitrile

Procedure

Using the procedure of Example 3 (a) with 4-(4-cyanophenyl)-2-butanone in place of 4-(4-chlorophenyl)-2-butanone, distillation under reduced pressure gave 1-methyl-3-(4-cyanophenyl)propylamine (b.p. 106°-112°/0.2 mm).

Workup

  1. distillationin place of 4-(4-chlorophenyl)-2-butanone, distillation under reduced pressure

Sources & evidence

ORD record
ord-ccf7fc4a18944e1f906524234cad3c55
Source dataset
uspto-grants-1980_07
Patent number
US04210653

Reaction notes

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