HCID 20231523, compound → HCID 20332295, compound

HRID 2057443Notes

Reaction equation

NC(CCCCCCCCC(N)C(C)C)C(C)C.[CH:19]1([CH:26]2[CH2:37][CH:36]=[CH:35][CH2:34][CH2:33][CH:32]=[CH:31][CH2:30][CH:29]([CH:38]3[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][CH2:39]3)[N:28]=[N:27]2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[NH2:27][CH:26]([CH:19]1[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1)[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH:29]([NH2:28])[CH:38]1[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][CH2:39]1

Participants

Reactant 2

HCID 20231523HCID 20231523, compound

HCID 57129806HCID 57129806, compound

Product 1

HCID 20332295HCID 20332295, compound

Procedure

The procedure described in (a) is repeated, starting from 106 g (0.3 mole) of 3,12-dicycloheptyl-1,2-diaza-1,5,9-cyclododecatriene (diastereoisomer mixture) and using correspondingly reduced amounts of catalyst and solvent, affording after purification by chromatography 63 g (58% of theory) of 1,10-diamino-1,10-dicycloheptyldecane as a colourless oil [nD20 =1.5018; IR spectrum (liquid) includes bands at 3390, 3310, 3618 cm-1 ]. PG,21

Workup

customaffording
customafter purification by chromatography 63 g (58% of theory) of 1,10-diamino-1,10-dicycloheptyldecane as a colourless oil [nD20 =1.5018; IR spectrum (liquid) includes bands at 3390, 3310, 3618 cm-1 ]

Sources & evidence

ORD record: ord-a123d3b8d4ac49cb84499de91bb728ff
Source dataset: uspto-grants-1980_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04210742

Reaction notes

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