HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetylacetone → Ethanone, 1-(4-amino-5-(4-fluorophenyl)-2-methyl-1H-pyrrol-3-yl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetylacetone | HCID 31261 | — |
| Reactant | 2-Amino-2-(4-fluorophenyl)acetonitrile | HCID 2735922 | — |
| Product | Ethanone, 1-(4-amino-5-(4-fluorophenyl)-2-methyl-1H-pyrrol-3-yl)- | HCID 41885 | — |
Reaction Steps
Starting from 2-amino-2-(p-fluorophenyl)acetonitrile and acetylacetone, the open-chain intermediate compound is obtained; b.p. 150° C./0.3 mm Hg. Overall yield of the title compound: 47%, m.p. 211°-12° C. (from ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211708 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-eb5eea0d69dd4a8c8fc1bb955a532ddc |
| Source note | uspto-grants-1980_07 |