3-Oxobutanal → HCID 20330052, compound

HRID 2057529Notes

Reaction equation

HRID 2057529 reaction equation
[NH2:1][CH:2]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][CH:6]=1)[C:3]#[N:4].[C:13]([CH2:16][CH:17]=O)(=[O:15])[CH3:14]>>[C:13]([C:16]1[C:3]([NH2:4])=[C:2]([C:5]2[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][CH:6]=2)[NH:1][CH:17]=1)(=[O:15])[CH3:14]

Participants

3

Reactant 2

HCID 46868603-OxobutanalHCID 13442977HCID 13442977, compound

Product 1

HCID 20330052HCID 20330052, compound

Procedure

Starting from 2-amino-2-(p-methoxyphenyl)acetonitrile and acetylacetaldehyde, the open-chain intermediate product is prepared, boiling at 180° C./0.03 mm Hg. Overall yield of the title compound: 44%, m.p. 198°-200° C. (from diethyl ether).

Workup

  1. customthe open-chain intermediate product is prepared

Sources & evidence

ORD record
ord-f2cd00db00d1493fbd8ca1394b1baf64
Source dataset
uspto-grants-1980_07
Patent number
US04211709

Reaction notes

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