HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Aminocephalosporanic acid → HCID 178476912, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Aminocephalosporanic acid | HCID 441328 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 178476915 | HCID 178476915 | — |
| Reactant | HCID 178527083 | HCID 178527083 | — |
| Product | HCID 178476912 | HCID 178476912 | — |
| Product | HCID 178511755 | HCID 178511755 | — |
Reaction Steps
Reaction of 7-aminocephalosporanic acid with 1-diethoxyphosphinylmethyltetrazole-5-thiol and 1-phosphonomethyltetrazole-5-thiol in the presence of 1 and 3 molecular equivalents of sodium bicarbonate, respectively, as described in Example 10 gives 7β-amino-3-(1-diethoxyphosphinylmethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and 7β-amino-3-(1-phosphonomethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211703 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-85eba8ef06964df7bfbc054b259a0d37 |
| Source note | uspto-grants-1980_07 |