HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54119678, compound → 2'-Fluoro-5-bromo-1-beta-D-arabinofuranosylcytosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54119678 | HCID 54119678 | — |
| Solvent | Ammonia | HCID 222 | — |
| Product | 2'-Fluoro-5-bromo-1-beta-D-arabinofuranosylcytosine | HCID 172392 | 81.3% |
Reaction Steps
1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-bromocytosine (1.0 g) is dissolved in saturated methanolic ammonia (100 ml) and the solution is left standing for 24 hours at room temperature. The solvent is removed in vacuo and the residue was crystallized from ethanol to give 560 mg of 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-bromocytosine, m.p. 201°-202°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211773 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-bab5abc43c2c408b95c115f7ddb52da4 |
| Source note | uspto-grants-1980_07 |