HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 7-(1-ethyl-2-methyl-3-indolyl)-7-(diphenylamino)furo[3,4-b]pyrazine-5(7H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Diphenylamine | HCID 11487 | — |
| Reactant | (1-Ethyl-2-methylindol-3-yl)-(2-carboxypyrazin-3-yl)ketone | HCID 20534320 | — |
| Product | 7-(1-ethyl-2-methyl-3-indolyl)-7-(diphenylamino)furo[3,4-b]pyrazine-5(7H)-one | HCID 20534277 | — |
Reaction Steps
A mixture containing 4 g. of 3-[(1-ethyl-2-methyl-3-indolyl)carbonyl]-2-pyrazinecarboxylic acid, 1.7 g. of diphenylamine and 15 ml. of acetic anhydride was stirred 1 hour at room temperature and then 30 minutes with gentle warming. The product, 7-(1-ethyl-2-methyl-3-indolyl)-7-(diphenylamino)furo[3,4-b]pyrazine-5(7H)-one was isolated by column chromatography as a red solid, m.p. 98°-100° C. A toluene solution of this product contacted with acidic clay or phenolic resin developed an orange image.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211872 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-19dbb90aed7948408e520c8505f4bb92 |
| Source note | uspto-grants-1980_07 |