反应详情

A mixture of 3.62 g. of 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoic acid (Example 7) and 25 ml. of ethanol-water (9:1) containing 0.400 g. of sodium hydroxide is stirred for 4 hours. The mixture is filtered and the residue washed with 10 ml. of ethanol-water (9:1) and dried in vacuo for 24 hours to yield sodium 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoate as a white solid.

1. additionA mixture of 3.62 g
2. filtrationThe mixture is filtered
3. washthe residue washed with 10 ml
4. dry with materialof ethanol-water (9:1) and dried in vacuo for 24 hours