HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron trifluoride etherate → Methyl 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | 4-[13-(4-Chlorophenyl)-12-tridecynylamino]benzoic acid | HCID 20330969 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoate | HCID 20330962 | — |
Reaction Steps
A solution of 50.5 g. of 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoic acid and 34.4 ml. of boron trifluoride etherate in 200 ml. of methanol is stirred under reflux for 44 hours, allowed to cool, and poured into 1.20 liters of ice-cold 5% aqueous sodium carbonate solution. The white solid is collected by filtration and recrystallized from benzene-ethanol to yield methyl 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211783 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-7a02d937274a4a2e90a283418358bd0a |
| Source note | uspto-grants-1980_07 |