HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lactic Acid → 1-Carboxyethyl 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lactic Acid | HCID 612 | — |
| Reactant | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| Reactant | 4-[13-(4-Chlorophenyl)-12-tridecynylamino]benzoic acid | HCID 20330969 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-Carboxyethyl 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoate | HCID 20331009 | — |
Reaction Steps
A flask containing 10.0 g. 4-[13-(4-chlorophenyl)tridec-12-ynylamino]benzoic acid, 3.3 g. lactic acid, 500 mg. toluene sulfonic acid and 500 ml. toluene is equipped with a Soxhlet extractor charged with activated 4A Linde molecular sieves. The solution is refluxed for 24 hours during which time the Soxhlet extractor is charged twice more with fresh sieves. The hot solution is filtered and left to cool, whereupon 1-carboxyethyl 4-[13-(4-chlorophenyl)tridec-12-ynylamino]-benzoate separates as off-white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211783 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-e7c6d8fe5be64174b6f1aa06388c89ab |
| Source note | uspto-grants-1980_07 |