HuagongsheHuagongshe Chemistry Print Report · For research reference only
Safrole → Safrole oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Safrole | HCID 5144 | — |
| Reactant | Perpropionic acid | HCID 65136 | — |
| Solvent | 1,1-Dichloropropane | HCID 6573 | — |
| Product | Safrole oxide | HCID 101123 | — |
Reaction Steps
48.82 g (0.3 mol) of 5-(2-propenyl)-1,3-benzodioxole were reacted with 45 g (0.1 mol) of a 20% strength solution of perpropionic acid in dichloropropane at 30° C. as described in Example 1. After a reaction time of 6 hours, the peracid conversion was 96%. 5-(Oxiranylmethyl)-1,3-benzodioxole was formed with a selectivity of 68%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04212809 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-0e6bb625f7d6498f99187530cf82f287 |
| Source note | uspto-grants-1980_07 |