2-Amino-5-chloropyridine → HCID 23345083, compound

Participants

Reaction Steps

A more efficient, novel method of synthesis of the insecticide comprises the steps (a) reacting 2-amino-5-chloropyridine with an equimolar amount of 2,6-dichlorobenzoyl isocyanate in a non-reactive organic solvent to obtain 1-(2,6-dichlorobenzoyl)-3-(5-chloro-2-pyridinyl)urea and (b) reacting this material with hydrogen peroxide in acetic acid to obtain the corresponding N-oxide, as illustrated specifically in Example 2 below.

Provenance & Evidence