Chloroacetyl chloride → HCID 20330174, compound

HRID 2057762Notes

Reaction equation

HRID 2057762 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([N+:10]([O-:12])=[O:11])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1.[Cl:20][CH2:21][C:22](Cl)=[O:23]>C(O)(=O)C>[Cl:20][CH2:21][C:22]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([N+:10]([O-:12])=[O:11])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1)=[O:23]

Participants

4

Reactant 2

HCID 6577Chloroacetyl chlorideHCID 20330193HCID 20330193, compound

Product 1

HCID 20330174HCID 20330174, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Using the method of Example 10, 5-amino-2-nitro-3-phenylbenzofuran is reacted with α-chloroacetyl chloride in acetic acid to provide 5-(α-chloroacetamido)-2-nitro-3-phenylbenzofuran.

Sources & evidence

ORD record
ord-4688492f3c4d4a0b81e8eac9786eb49c
Source dataset
uspto-grants-1980_07
Patent number
US04212865

Reaction notes

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