Benzoyl chloride → HCID 20330184, compound

HRID 2057766Notes

Reaction equation

HRID 2057766 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([N+:10]([O-:12])=[O:11])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1.[C:20](Cl)(=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>N1C=CC=CC=1>[C:20]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([N+:10]([O-:12])=[O:11])=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[CH:19]=1)(=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 20330193HCID 20330193, compound

Product 1

HCID 20330184HCID 20330184, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a solution of 0.75 g. of 5-amino-2-nitro-3-phenylbenzofuran in 5 ml. of pyridine is added 1 ml. of benzoyl chloride. The mixture is heated on a steam bath for about 1 hour, then decanted into 50 ml. of 2 N hydrochloric acid. A yellow residue forms which is recrystallized from a mixture of isopropanol, methanol and water to provide yellow crystals of 5-benzamido-2-nitro-3-phenylbenzofuran having the structure ##STR11##

Workup

  1. temperatureThe mixture is heated on a steam bath for about 1 hour
  2. customdecanted into 50 ml
  3. customA yellow residue forms which is recrystallized from a mixture of isopropanol, methanol and water

Sources & evidence

ORD record
ord-7601961f4b7b49f0941a79271698ecf8
Source dataset
uspto-grants-1980_07
Patent number
US04212865

Reaction notes

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