HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Octanediamine → N-cyano-N'-methyl-N"-(8-aminooctyl)guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Octanediamine | HCID 24250 | — |
| Reactant | 1-Cyano-2,3-dimethylisothiourea | HCID 111103 | — |
| Product | N-cyano-N'-methyl-N"-(8-aminooctyl)guanidine | HCID 178484956 | 58.4% |
Reaction Steps
A mixture of 1,8-diaminooctane (14.1 g) with N-cyano-N'-methyl-S-methyl isothiourea (5.2 g) was maintained at 60° for 5 hours to give a solid product which was washed with ether and recrystallised from acetonitrile/ether to give N-cyano-N'-methyl-N"-(8-aminooctyl)guanidine (5.3 g) m.p. 81°-83°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04212875 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-368076ac21dc4e4492a44d9abb98b354 |
| Source note | uspto-grants-1980_07 |