Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → Ethyl 5-phenylbenzofuran-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Diethyl bromomalonate | HCID 69637 | — |
| 반응물 | 4-Hydroxy-(1,1'-biphenyl)-3-carbaldehyde | HCID 12264658 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | Ethyl 5-phenylbenzofuran-2-carboxylate | HCID 20329644 | — |
반응 단계
A mixture of 0.99 g of 5A, 0.96 g of diethyl bromomalonate and 1.25 g of anhydrous potassium carbonate in 20 ml of 2-butanone, was refluxed for 10 hours. The solvent was evaporated under reduced pressure. The residue was cooled, mixed with 100 ml of water and extracted with ether. The extract was washed with cold 5% sodium hydroxide solution and water and then concentrated under reduced pressure. The residue was recrystallized from ethanol to give ethyl 5-phenylbenzofuran-2-carboxylate (10B), as white crystals, mp: 109°-110° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04213999 |
| 출처 데이터셋 | uspto-grants-1980_07 |
| ORD ID | ord-61be619ad6454a789e1fecfc9e130eae |
| 출처 메모 | uspto-grants-1980_07 |