Potassium Hydroxide → 5-(4-Acetylphenyl)-2-benzofurancarboxylic acid

HRID 2057972Notes

Reaction equation

HRID 2057972 reaction equation

[C:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]3[O:17][C:16]([C:18]([O:20]CC)=[O:19])=[CH:15][C:14]=3[CH:23]=2)=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[OH-].[K+]>C(O)C>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:11]=[CH:12][C:13]3[O:17][C:16]([C:18]([OH:20])=[O:19])=[CH:15][C:14]=3[CH:23]=2)=[CH:8][CH:9]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 14797Potassium Hydroxide

HCID 20329647Ethyl 5-(4-acetylphenyl)benzofuran-2-carboxylate

Product 1

HCID 203296455-(4-Acetylphenyl)-2-benzofurancarboxylic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10A was treated with potassium hydroxide in ethanol to give 10, mp: 264°-266° C.

Sources & evidence

ORD record: ord-91a4f605c2434eb2bc223e64af39a369
Source dataset: uspto-grants-1980_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04213998

Reaction notes

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