3-Iodomethyl-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester → 3-[4-(5-Chloro-pyrimidin-2-yl)-phenoxymethyl]-1-(2-methoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester
Reaction equation
[CH2:15]([CH3:16])[O:17][C:18](=[O:19])[C:20]1([CH2:35][I:36])[CH2:21][N:22]([C:25]([c:26]2[c:27]([O:32][CH3:33])[cH:28][cH:29][cH:30][cH:31]2)=[O:34])[CH2:23][CH2:24]1.[Cl:1][c:2]1[cH:3][n:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([OH:14])[cH:12][cH:13]2)[n:6][cH:7]1>>[Cl:1][c:2]1[cH:3][n:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([O:14][CH2:35][C:20]3([C:18]([O:17][CH2:15][CH3:16])=[O:19])[CH2:21][N:22]([C:25]([c:26]4[c:27]([O:32][CH3:33])[cH:28][cH:29][cH:30][cH:31]4)=[O:34])[CH2:23][CH2:24]3)[cH:12][cH:13]2)[n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-b30065ab77484122a14752cd9230eff3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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