HCID 131711831, compound → HCID 178480564, compound

HRID 2058041Notes

Reaction equation

HRID 2058041 reaction equation
Br.[Cl:2][C:3]1[CH:22]=[CH:21][C:6]([C:7]([CH:9]([S:14][C:15]2[N:16]([CH3:20])[CH:17]=[CH:18][N:19]=2)[CH2:10][C:11]([OH:13])=[O:12])=[O:8])=[CH:5][CH:4]=1>O>[OH-:8].[C:11]([CH2:10][CH:9]1[S:14][C:15]2[N:16]([CH3:20])[CH:17]=[CH:18][N+:19]=2[C:7]1([C:6]1[CH:5]=[CH:4][C:3]([Cl:2])=[CH:22][CH:21]=1)[OH:8])([OH:13])=[O:12]

Participants

3

Reactant 1

HCID 131711831HCID 131711831, compound

Product 1

HCID 178480564HCID 178480564, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Finely ground 3-(p-chlorobenzoyl)-3-(1-methylimidazol-2-ylthio)propionic acid, hydrobromide, (6.0 g.) is added to 250 ml. of water and the mixture stirred for 20 min. The solid is collected and dried at room temperature. The crude material which weighs 4.6 g. and melts at 160°-2° is recrystallized from acetone. The recrystallized material melts at 161°-3°.

Workup

  1. customThe solid is collected
  2. customdried at room temperature
  3. customand melts at 160°-2° is recrystallized from acetone

Sources & evidence

ORD record
ord-aa4d4e6aa75e482a8082da23171b76cd
Source dataset
uspto-grants-1980_07
Patent number
US04214089

Reaction notes

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