HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2058111Generated: November 1, 2026
4-Toluenesulfonyl chloride → HCID 1712496, compound
https://huagongshe.com/reaction/2058111
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | 3-Hydroxypyridine | HCID 7971 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 1712496 | HCID 1712496 | — |
Reaction Steps
Equimolar portions (0.106 moles) of 3-hydroxypyridine, sodium hydroxide and p-toluenesulfonyl chloride were combined in 100 ml of water and stirred at 50° C. for 2.5 hours. The aqueous solution was extracted with chloroform, dried over sodium sulfate and distilled to yield an oil which crystallized on standing. Recrystallization from cyclohexane yielded a white solid, mp 76°-78° C., lit. mp 79° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04215003 |
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| Source dataset | uspto-grants-1980_07 |
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| ORD ID | ord-54f8d1de04464e289a3eb6d98fa36fa5 |
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| Source note | uspto-grants-1980_07 |
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