Hydrochloric Acid → HCID 54716192, compound

Participants

Reaction Steps

A stirred mixture of 0.5 g. of 1-ethyl-1,2-dihydro-7-methyl-2-oxo-4-(1-pyrrolidinyl)-1,8-naphthyridine-3-carbonitrile in 15 ml. of 20% aqueous sodium hydroxide containing 15 ml. of ethanol was heated under reflux for 3 hours. The solution was cooled and was acidified with concentrated hydrochloric acid. The precipitate which formed was collected, air dried and was recrystallized from ethanol to afford 0.2 g. of the title compound, m.p. 274°-6° C.

Provenance & Evidence