Tetrafluoroethylene → 2-(1,1,2,2-Tetrafluoroethylthio)imidazole

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The appropriate R1 moiety can then be introduced onto the sulfur by a suitable alkylating agent such as tetrafluoroethylene or difluorocarbene. For example, the 2-mercaptoimidazole derivative of Reaction (2) can be reacted with tetrafluoroethylene to form the 2-(1,1,2,2-tetrafluoroethylthio)imidazole derivative. ##STR10## The reaction is carried out under heat and pressure with a slight excess of the fluorocarbon reactant. Typically, the reaction is carried out in a closed reaction vessel at a temperature of 50° C. at an initial pressure of about 50 p.s.i. which falls to about 13 p.s.i. as the reaction proceeds. Similar addition reactions of tetrafluoroethylene and other fluorinated olefins are described by England, D. C. et al., J. Am. Chem. Soc., 82, 5116 (1960) and Rapp, K. E., et. al., J. Am. Chem. Soc., 72, 3642 (1950). Within the context of the invention, tetrafluoroethylene and other fluorinated olefins used are considered alkylating agents.

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