HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → rac-(1R,2R)-2-(dimethylamino)cyclohexan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Cyclohexene oxide | HCID 9246 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | rac-(1R,2R)-2-(dimethylamino)cyclohexan-1-ol | HCID 15560793 | — |
Reaction Steps
This compound was previously prepared from cyclohexene oxide and dimethylamine in benzene at room temperature for 14 days in 95% yield, b.p. 90°(20 mm): J. Chem. Soc., 4835 (1965); or in autoclave: C. A. 67, 63899 d, Rocz. Chem. 41, 541 (1967) b.p. 88° (14 mm); also Bull. Soc. Chim. France, 850 (1947): hydrochloride and resolution reported.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04215114 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-834d429acfe84271ada8bff2d584ff24 |
| Source note | uspto-grants-1980_07 |