2,4-Dibromobenzyl chloride → 1-[2-(2,4-Dibromobenzyloxy)-3-(3,4-dichloroanilino)-propyl]-imidazole

HRID 2058323Notes

Reaction equation

HRID 2058323 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[Cl:18])[NH:5][CH2:6][CH:7]([OH:14])[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1.[Br:19][C:20]1[CH:27]=[C:26]([Br:28])[CH:25]=[CH:24][C:21]=1[CH2:22]Cl>>[Br:19][C:20]1[CH:27]=[C:26]([Br:28])[CH:25]=[CH:24][C:21]=1[CH2:22][O:14][CH:7]([CH2:6][NH:5][C:4]1[CH:15]=[CH:16][C:17]([Cl:18])=[C:2]([Cl:1])[CH:3]=1)[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1

Participants

3

Reactant 2

HCID 202707092,4-Dibromobenzyl chlorideHCID 233502001-[3-(3,4-Dichloroanilino)-2-hydroxypropyl]imidazole

Product 1

HCID 233502071-[2-(2,4-Dibromobenzyloxy)-3-(3,4-dichloroanilino)-propyl]-imidazole

Procedure

Reaction of 1-[3-(3,4-dichloroanilino)-2-hydroxypropyl]-imidazole with 2,4-dibromobenzyl chloride yields 1-[2-(2,4-dibromobenzyloxy)-3-(3,4-dichloroanilino)-propyl]-imidazole.

Sources & evidence

ORD record
ord-007dc2d2bf1040ac88e7291139ea5cc7
Source dataset
uspto-grants-1980_07
Patent number
US04215220

Reaction notes

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