4-Morpholinecarbonyl chloride → Methyl 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylate
Reaction equation
[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH2:10][CH:11]([C:15](=[O:16])[O:17][CH3:18])[CH2:12][NH:13][CH2:14]2)[cH:7][cH:8]1)([F:19])[F:20].[O:21]1[CH2:22][CH2:23][N:24]([C:27](=[O:28])[Cl:29])[CH2:25][CH2:26]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH2:10][CH:11]([C:15](=[O:16])[O:17][CH3:18])[CH2:12][N:13]([C:27]([N:24]3[CH2:23][CH2:22][O:21][CH2:26][CH2:25]3)=[O:28])[CH2:14]2)[cH:7][cH:8]1)([F:19])[F:20]Participants
3
Sources & evidence
- ORD record
- ord-34c8853703814bb0a68f56b47bf09cdb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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