反应详情

Bromomethylcycloheptane (5.3 g, 0.0278 mol) was added dropwise to a stirred solution of potassium t-butoxide (3.1 g, 0.0277 mol) and imidazole (1.9 g, 0.0279 mol) in dry n-butanol (50 ml) maintained at 100° and under dry nitrogen. After the addition (~20 mins) the temperature of the reaction mixture was raised to boiling. The reaction mixture was then stirred and boiled for 7 h and then cooled.

1. temperaturemaintained at 100° and under dry nitrogen
2. additionAfter the addition (~20 mins) the temperature of the reaction mixture
3. temperaturewas raised
4. temperaturecooled