HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 1-(2-Cyclooctenylmethyl)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | 2-Cyclooctene 1-bromomethane | HCID 70502991 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-(2-Cyclooctenylmethyl)imidazole | HCID 54475103 | — |
Reaction Steps
2-Cyclooctene-1-bromomethane (0.7 g, 0.0034 mol) was added dropwise to a boiling solution of imidazole (0.24 g, 0.0035 mol) and potassium t-butoxide (0.39 g, 0.0035 mol) in dry n-butanol, under dry nitrogen. After the addition, the reaction mixture was stirred and heated under reflux for 1 h. The pure product was obtained as described in Example 4, b.p. 108°-110°/0.02 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04317830 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-420205c0f03e4e9f80603adcca24db83 |
| Source note | uspto-grants-1982_03 |