Imidazole → HCID 20550242, compound

HRID 2058446Notes

Reaction equation

HRID 2058446 reaction equation
Cl[CH2:2][CH2:3][CH:4]1[CH2:9][CH2:8][CH:7]=[CH:6][CH2:5]1.CC(C)([O-])C.[K+].[NH:16]1[CH:20]=[CH:19][N:18]=[CH:17]1>C(O)CCC>[CH:4]1([CH2:3][CH2:2][N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)[CH2:9][CH2:8][CH:7]=[CH:6][CH2:5]1

Participants

5

Reactant 3

HCID 795ImidazoleHCID 12480857HCID 12480857, compoundHCID 23665647Potassium tert-butoxide

Product 1

HCID 20550242HCID 20550242, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

1-Chloro-2-(cyclohex-3-enyl)ethane (38.0 g, 0.265 mol) was added dropwise to a stirred, boiling solution of potassium tert-butoxide (30.0 g, 0.27 mol) and imidazole (18.0 g, 0.265 mol) in dry butan-1-ol. Following the addition, the reaction mixture was stirred and heated under reflux for 4 h.

Workup

  1. additionthe addition
  2. temperatureheated
  3. temperatureunder reflux for 4 h.

Sources & evidence

ORD record
ord-c8aebcbed4b84e2aa934e0a3143dd20f
Source dataset
uspto-grants-1982_03
Patent number
US04317830

Reaction notes

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