反应详情

1-Cyclooctylmethylimidazole (~0.3 g) was dissolved in dry ether (30 ml), when a stream of dry hydrogen chloride was passed through the solution at -20° C. The resulting white precipitate was filtered off under dry nitrogen and recrystallised from ethyl acetate/petroleum ether (b.p. 40°-60° C.) to afford 1-cyclooctylmethylimidazole hydrochloride as a white solid, m.p. 20°-22° C.

1. customwas passed through the solution at -20° C
2. filtrationThe resulting white precipitate was filtered off under dry nitrogen
3. customrecrystallised from ethyl acetate/petroleum ether (b.p. 40°-60° C.)