Acetic Anhydride → HCID 12911925, compound

Participants

Reaction Steps

2.84 g of 3-amino-7a,8,9,10,11,11a-hexahydro-4-oxo-4H-pyrido[3,2,1-jk]carbazole-5-carboxylic acid was dissolved in 50 ml of a 2% aqueous potassium hydroxide, and acetic anhydride was added dropwise thereto while ice cooling whereby orange-colored crystals were precipitated. The resulting crystals were separated by filtration, washed with water and recrystallized from dimethylformamide-water to obtain 3 g of 3-acetylamino-7a,8,9,10,11,11a-hexahydro-4-oxo-4H-pyrido[3,2,1-jk]carbazole-5-carboxylic acid having a melting point of 187°-190° C.

Provenance & Evidence