HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 1,3-dimethyl-4-nitro-1H-pyrazole-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile | HCID 96507 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1,3-dimethyl-4-nitro-1H-pyrazole-5-carboxamide | HCID 1229764 | — |
Reaction Steps
27.2 g of 1,3-dimethyl-4-nitropyrazole-5-carbonitrile and 65 ml of concentrated sulfuric acid are stirred at 80° C. for 6 hours. The mixture is poured into 700 g of ice and water, and the precipitate is filtered off and suspended in ice-water; the suspension is neutralized with sodium bicarbonate to yield 27.3 g of 1,3-dimethyl-4-nitropyrazole-5-carboxamide, mp 164° to 165° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04317823 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-58589026adbf4087aa1210eba6aabe36 |
| Source note | uspto-grants-1982_03 |