Methanol → HCID 10474496, compound

Participants

Reaction Steps

A solution of 25 g (0.15 mol) of 2-nitro-benzoic acid in 75 ml of methanol was added dropwise to a boiling solution of 31 g (0.15 mol) of dicyclohexyl-carbodiimide and 8 ml of triethylamine in 300 ml of methanol. The reaction mixture was heated under reflux for 2 hours and stirred at room temperature overnight. After distilling off the solvent in vacuo, the residue was recrystallized from isopropanol. 25 g (45% of theory) of N-(2-nitrobenzoyl)-N,N'-dicyclohexyl-urea of melting point 134° C. were obtained.

Provenance & Evidence