HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15136297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ketene | HCID 10038 | — |
| Reactant | Benzyl 3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate | HCID 12804725 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15136297 | HCID 15136297 | — |
Reaction Steps
A solution of benzyl 1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylate (13 mg, 0.05 mmol) in anhydrous CH2Cl2 (1 ml) is cooled in an ice-bath and treated with triethylamine (Et3N) (7 μl, 0.05 mmol). Ketene is passed through the resulting solution for 10 mins. The solvent and excess ketene are removed in vacuo to leave crude benzyl 3-acetoxy-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04318912 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-d9331aafcae5464387dea32d55a84ff3 |
| Source note | uspto-grants-1982_03 |