HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylhydrazine → 1-Methyl-N5-[3-[3-[(dimethylamino)methyl]phenoxy]propyl]-1H-1,2,4-triazole-3,5-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylhydrazine | HCID 6061 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | N-Cyano-N-[3-[3-[(dimethylamino)methyl]phenoxy]propyl]carbamimidothioic acid methyl ester | HCID 54462898 | — |
| Product | 1-Methyl-N5-[3-[3-[(dimethylamino)methyl]phenoxy]propyl]-1H-1,2,4-triazole-3,5-diamine | HCID 13789853 | — |
Reaction Steps
N-Cyano-N-[3-[3-[(dimethylamino)methyl]phenoxy]propyl]carbamimidothioic acid methyl ester (1.5 g) and N-methylhydrazine (1.2 g) in dimethylformamide (15 ml) were heated at 40° for 24 hours. The solvent was removed, and the residue was triturated with ether to yield the title compound as a white solid (1.0 g) m.p. 95°-96.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04318913 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-c613acb106594ceaa82bf4e2c0602c6e |
| Source note | uspto-grants-1982_03 |