Phthalic Anhydride → HCID 12961629, compound

HRID 2058781Notes

Reaction equation

HRID 2058781 reaction equation
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[CH3:12][N:13]([C:15]1[O:16][C:17]2[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=2[N:19]=1)[NH2:14]>C(Cl)(Cl)Cl>[C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[C:1]([NH:14][N:13]([C:15]1[O:16][C:17]2[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=2[N:19]=1)[CH3:12])=[O:11])([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 6811Phthalic AnhydrideHCID 129616282-(1-Methylhydrazino)benzoxazole

Product 1

HCID 12961629HCID 12961629, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A suspension of 5.2 g. of phthalic anhydride in 75 ml. of chloroform is stirred and treated with 5.7 g. of 2-(1-methylhydrazino)benzoxazole. A clear yellow solution results and the temperature drops several degrees, then rises to 33+ C. After about 15 min. precipitation of a solid begins. An additional 200 ml. of chloroform is added and the mixture is stirred overnight. The solid is filtered, washed with chloroform and dried to give 8.6 g. of product, m.p. 140°-142°.

Workup

  1. additionA suspension of 5.2 g
  2. additiontreated with 5.7 g
  3. customA clear yellow solution results
  4. customAfter about 15 min. precipitation of a solid
  5. additionof chloroform is added
  6. filtrationThe solid is filtered
  7. washwashed with chloroform
  8. customdried
  9. customto give 8.6 g

Sources & evidence

ORD record
ord-03c547f0df514eb9aad55ba142266606
Source dataset
uspto-grants-1982_03
Patent number
US04319026

Reaction notes

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