Dichloromethane → 4-(1-Phenyl-1-(3-oxo-1-butyn-1-yl)methylene)-piperidine-1-carboxylic Acid Tert-Butyl Ester

HRID 205879Notes

Reaction equation

HRID 205879 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[C:14]([C:15]#[C:16][CH:17]([CH3:18])[OH:19])[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:12][CH2:13]1.[Cl:26][CH2:27][Cl:28].[O:29]=[Mn:30]=[O:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[C:14]([C:15]#[C:16][C:17]([CH3:18])=[O:19])[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 14801Manganese dioxideHCID 866219574-(1-Phenyl-1-(3-hydroxy-1-butyn-1-yl)-methylene)-piperidine-1-carboxylic Acid Tert-Butyl Ester

Product 1

HCID 865943864-(1-Phenyl-1-(3-oxo-1-butyn-1-yl)methylene)-piperidine-1-carboxylic Acid Tert-Butyl Ester

Sources & evidence

ORD record
ord-9c66884a4e6742b28b1bb540ecd94fb6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…