HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2058796Generated: October 31, 2026
Sulfuric Acid → 3-(Piperidino)-acrylonitrile
https://huagongshe.com/reaction/2058796
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 12196056 | HCID 12196056 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(Piperidino)-acrylonitrile | HCID 54499125 | 59.2% |
Reaction Steps
30.3 g (0.25 mol) of sodium-3-hydroxyethylnitrile (content 75%) is added to a suspension of piperidine sulfate (prepared from 29.8 g (0.35 mol) of piperidine and 17.15 g (0.175 mol) of sulfuric acid) in 200 ml of methanol and stirred for 24 hours at 25° C. After working up as in Example 55, 28.2 g of 3-piperidinoacrylonitrile was obtained (82.9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04319024 |
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| Source dataset | uspto-grants-1982_03 |
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| ORD ID | ord-8809abe744b1426689fbd5052a90ba53 |
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| Source note | uspto-grants-1982_03 |
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