Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Triethylamine hydrochloride | HCID 11130 | — |
| Reactant | Sodium 3-hydroxyacrylonitrile | HCID 86738287 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(Piperidino)-acrylonitrile | HCID 54499125 | 79% |
Reaction Steps
30.3 g (0.25 mol) of sodium-3-hydroxyacrylonitrile (content 75%) is added to a suspension of 41.3 g (0.3 mol) of triethylamine hydrochloride and 21.3 g (0.25 mol) of piperidine in 200 ml of ethanol and maintained for 24 h at 25° C. After working up as in Example 56, 26.9 g of 3-piperidinoacrylonitrile is obtained (79.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04319024 |
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| Source dataset | uspto-grants-1982_03 |
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| ORD ID | ord-63981bc8ff3c4bc69da86ede7ab92025 |
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| Source note | uspto-grants-1982_03 |
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